Sildenafil in the Treatment of Erectile Dysfunction
Title: Sildenafil in the Treatment of Erectile Dysfunction , By: Rose, Verna L., American Family Physician, 0002838X, 07/01/98, Vol. 58, Issue 1
Section: Clinical Briefs
The U.S. Food and Drug Administration has approved the oral therapy sildenafil (Viagra) in the treatment of erectile dysfunction. Sildenafil is the first in a new class of medications known as phosphodiesterase type 5 ‘inhibitors that improve blood flow to the penis. Sildenafil is taken about one hour before anticipated sexual activity.
In clinical trials of men with mild, moderate or complete erectile dysfunction (mean age: 55 years), the drug was shown to be effective in approximately seven out of 10 men overall and was effective across patients with erect fie dysfunction attributed to diabetes, spinal cord injury or psychologic causes, among others Most of the study subjects had experienced erectile dysfunction for an average of five years before entering the clinical trials.
Sildenafil was well tolerated. The most common side effects seen in the men in the clinical trials were headache, facial flushing and indigestion. The drug is contraindicated in patients receiving nitrates in any form, including nitroglycerin.
The American Foundation for Urologic Disease (AFUD) has issued a statement regarding the approval of sildenafil for the treatment of erectile dysfunction. AFUD notes that only 5 to 10 percent of men with impotence currently seek treatment, and AFUD hopes that approval of the drug will encourage more men to visit their physicians for consultation. They suggest that men “take this opportunity to openly discuss all symptoms, causes and treatment options with their physicians and have an overall health examination to select the most appropriate course of treatment.”
~~~~~~~~
By VERNA L. ROSE
Copyright of American Family Physician is the property of American Academy of Family Physicians and its content may not be copied or e-mailed to multiple sites or posted to a listserv without the copyright holder`s express written permission. However, users may print, download, or e-mail articles for individual use.
Source: American Family Physician, 07/01/98, Vol. 58 Issue 1, p268, 1p
$anchor$basketball Betting,final Four,final Four Betting,final Four Gambling,final Four Sports Book,final Four Sportsbook,march Madness,march Madness Betting,march Madness Gambling,march Madness Sports Book,march Madness Sportsbook,ncaa,ncaa Betting,…
$anchor$basketball Betting,final Four,final Four Betting,final Four Gambling,final Four Sports Book,final Four Sportsbook,march Madness,march Madness Betting,march Madness Gambling,march Madness Sports Book,march Madness Sportsbook,ncaa,ncaa Betting,nc…
Trackback by $anchor$basketball Betting,final Four,final Four Betting,final Four Gambling,final Four Sports Book,final Four Sportsbook,march Madness,march Madness Betting,march Madness Gambling,march Madness Sports Book,march Madness Sportsbook,ncaa,ncaa Betting,ncaa — March 10, 2008 @ 1:09 pm
Rosellesportscircle1543$anchor$basketball Betting,final Four,final Four Betting,final Four Gambling,final Four Sports Book,final Four Sportsbook,march Madness,march Madness Betting,march Madness Gambling,march Madness Sports Book,march Madness Sports…
Rosellesportscircle1543$anchor$basketball Betting,final Four,final Four Betting,final Four Gambling,final Four Sports Book,final Four Sportsbook,march Madness,march Madness Betting,march Madness Gambling,march Madness Sports Book,march Madness Sportsbo…
Trackback by Rosellesportscircle1543$anchor$basketball Betting,final Four,final Four Betting,final Four Gambling,final Four Sports Book,final Four Sportsbook,march Madness,march Madness Betting,march Madness Gambling,march Madness Sports Book,march Madness Sportsbook, — March 15, 2008 @ 9:46 am